Tag Archives: Disorder

Excessive Threat of Sleep Dysfunction Burden in Transgender Youth: Ronald Gavidia, MD, MS

WATCH TIME: 4 minutes “The most important part is to inform people that the transgender community has more sleep disorders than the cisgender population and the use of gender affirming therapy may help.” Presently, there has been few reported studies on sleep disorders in individuals who identify as transgender or gender-nonconforming (TGNC). In addition, the […]

Pharmacological interventions for insomnia dysfunction in adults

A meta-analysis published in 2022 by Franco de Crescenzo and colleagues 1 De Crescenzo F D’Alò GL Ostinelli EG et al. Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis. Lancet. 2022; 400: 170-184 suggested poor efficacy of pharmacotherapeutics in the treatment […]

Cancer Pain and Opioid Use Disorder

ABSTRACT Opioid use disorder (OUD) is increasingly recognized and co-present in patients with cancer. Unfortunately, OUD is not addressed or treated adequately in oncology settings. In addition, patients with cancer-related pain treated with narcotic pain medications are at risk for nonmedical opioid use (NMOU). More than two-thirds of patients with advanced cancer have pain. Both […]

Daridorexant Secure, Efficient for Insomnia Dysfunction

FRIDAY, Feb. 4, 2022 (HealthDay News) — Daridorexant (50 mg) improves both nighttime symptoms and daytime functioning in people with insomnia disorder, according to a study published in the Feb. 1 issue of The Lancet Neurology. Emmanuel Mignot, M.D., from the Stanford Center for Sleep Research and Medicine in Palo Alto, California, and colleagues conducted […]

I haven’t slept for 4 YEARS as a consequence of uncommon dysfunction

IF you’ve ever found yourself tossing and turning at 3am, staring at the clock and wishing for sleep, spare a thought for London mum Malgorzata Sliwinska. The 39-year-old says it’s been FOUR YEARS since she had a decent night of shut-eye, thanks to a rare sleep disorder called somniphobia. 4 Malgorzata Sliwinska used to be […]

FLUID examine: examine protocol for an open-label, single-centre pilot examine to analyze the efFect of Lemborexant on sleep administration in Japanese sUbjects aged 50 years and older with Insomnia Dysfunction

This article was originally published here BMJ Open. 2021 Nov 26;11(11):e054885. doi: 10.1136/bmjopen-2021-054885. ABSTRACT INTRODUCTION: Bidirectional associations have been reported between sleep disturbance and both cognitive impairment, including Alzheimer’s disease and amyloid beta-peptide (Aβ) accumulation. These relationships can be explained by the glymphatic system, which acts as a garbage drainage system in the brain. As […]